Once these are delivered, she asks for a number of ingredients to make the cure. She will say that she requires five empty grand soul gems before she will help with the cure. Travel to Drakelowe and talk to the witch Melisande. Hassildor wants the cure, and tells of a witch that lives near the Corbolo river, south of Cheydinhal in Drakelowe.

He lives with the disease, but his wife, Rona Hassildor, could not, and slipped into a coma. Once Hassildor comes, he explains that he and his wife are vampires. Upon arrival at Castle Skingrad, find Janus Hassildor's steward, Hal-Liurz, in order to contact Hassildor. He will refer the Hero to Count Hassildor of Skingrad. The first step is to talk to Raminus Polus in the Arcane University, located in the Imperial City about vampirism. While this is normally a permanent condition, it is possible to cure the disease, even after becoming a full vampire. If the Hero is bitten by a vampire, contracts Porphyric Hemophilia, and does not cure themselves of the disease (using the same methods by which they could cure any other disease) within three days, they will become a vampire.